Sanctuary Hotel and Spa is in an ideal South Beach setting for those who want to be away from it all but in the middle of it all. Our four star boutique hotel is located steps away from Collins Avenue, the Fillmore at Jackie Gleason Theater, Miami Beach Convention Center, New World Symphony, Washington Ave., and Ocean Drive. Whether your trip is business or leisure our knowledgeable staffs will guide your South Beach experience and make sure that exceptional service is unlike any other Miami Beach Hotel.